-
Research article -
Medical Published: Jun 08, 2020
Analyzing the Effectiveness of Extraperitoneal Route versus Transperitoneal Route of Colostomy Related Complications: Systematic Review and Meta-Analysis
The colostomy is an opening in the large intestine that creates many surgical events [1]. This cut opening happens due to the drawing of the healthy end of the large intestine with an incision in the forward abdominal wall. The opening happens with the attached stoma application, and it provides…
-Isah Adamu Danbala, Wang Xiaogang, Xue Xiaofei, Qu Jianguo, Zakari Shaibu, and Dang Shengchun
-
Review article -
Medical Published: Jun 05, 2020
Hyperhemolytic Syndrome Due to Hemoglobinopathy in Sub-Saharan Africa
Globally, hemoglobinopathies remains a common genetic disorder of blood with highest prevalence recorded in the developing countries particularly those of the sub-Saharan Africa. Although there is progress towards a permanent cure, life-long transfusion therapy remains a life-saving option for patients. While the safety of blood to patients are established in…
-Alphonsus O. Ogbuabor, Peter U. Achukwu, Silas A. Ufelle, and Daniel C. Ogbuabor
-
Opinion -
Lifesciences Published: Jun 05, 2020
The USA New Green Deal Will Create Over 18 Million Jobs
The Green New Deal (GND) is a proposed package of USA legislation designed to address climate change, economic inequality, and other issues. The name is derived from the New Deal, a set of social and economic reforms and public works projects undertaken by USA President Franklin Roosevelt in response to…
-Roger H. Bezdek
-
Research article -
Lifesciences Published: May 07, 2020
Re-validating Therapeutic Relevance of Monoclonal Antibody Therapies using Computerized and Digital Signal Processing-based Bioinformatics Approach
Monoclonal antibody therapies have emerged as the mainstay in the treatment of variety of ailments. As proteins with discrete amino acid residues, they qualify for computerized, sequence information-, bioinformatics- and digital signal processing-based assessments. These assessments include resistance resulting from single-point mutation S492R in the ectodomain of the Epidermal Growth…
-Norbert Nwankwo, Ngozika Njoku, Ignatius Okafor, Michael Adikwu, Emmanuel Ibezim, Nnenna Ibezim, Mat
-
Research article -
Lifesciences Published: May 05, 2020
Chip-seq and RNA-seq Data for the Identification of Functional Sub-pathways: A Proof of Consept in Lung Cancer
High-throughput technologies, such as chromatin immunoprecipitation (ChIP) with massively parallel sequencing (ChIP-seq) have enabled cost and time efficient generation of immense amount of genome data. The advent of advanced sequencing techniques allowed biologists and bioinformaticians to investigate biological aspects of cell function and understand or reveal unexplored disease etiologies.
-Xanthoula Atsalaki, Lefteris Koumakis, George Potamias, Manolis Tsiknakis