Journal of Bioinformatics, Computational and Systems Biology

Previous Issue

  • Research article - Lifesciences Published: Sep 05, 2018

    Investigating Oncological Properties of Transactivation Domain of the p53 using Computerized Digital Signal Processing-based Bioinformatics Technique: A Demonstration

    Good understanding of disease processes is needed to proffer therapeutic solutions. Earlier solutions including Anti-Microbial Resistance (AMR), which engage assay techniques such as Culture and Sensitivity tests have been provided. These techniques utilize slow and resources-consuming clinical techniques. However, computerized procedures including Discrete Fourier Transform (DFT)-based, Digital Signal Processing (DSP)…

    -Nwankwo N, Njoku N, Okafor IS, Adikwu M, Ibezim E, and Ibezim N

  • Research article - Lifesciences Published: Nov 30, 2018

    PanGeneHome : A Web Interface to Analyze Microbial Pangenomes

    Recent advances in DNA sequencing technology led a rapid accumulation of microbial genomic data. Due to their inherent genomic plasticity, microbial species are now described throughout their pangenome and not just through a unique reference genome; for a review. A microbial pangenome is composed of core genes (shared by all…

    -Camille Loiseau, Victor Hatte, Charlotte Andrieu, Loic Barlet, Audric Cologne, Romain De Oliveira, L

  • Research article - Lifesciences Published: Aug 30, 2018

    Amino Acid Scales: The Driving Force in the Translation of Genomic Information into Phenotypic Characteristics

    Recently, the Anti-Microbial Resistance (AMR) Challenge for a point-of-care diagnostic device was rolled out. This challenge requested for submissions that may have focused on the clinical procedure (in vivo or in vitro assay). This may be as a result of the fact that little is understood about the ability of…

    -Norbert Nwankwo and Ngozika Njoku

  • Research article - Lifesciences Published: Aug 04, 2018

    The Cell Embodies Standard Engineering Principles

    In the last several decades, different engineering disciplines have explored ways to harness biology. Engineers have looked to biology not just for medical applications, but also for production of biomimetic materials and technologies, neural network processing algorithms, and even computer networking. These engineering applications of biological phenomena are made possible…

    -Curtis E. Hrischuk and Gregory T. Reeves

  • Research article - Lifesciences Published: Sep 06, 2018

    Computer-Aided Druggability Detector: A Computerized Apparatus for Quickening Drug Discovery Processes

    It has been reported that less than one percent of drug discovery projects get into the market, and that failure at the late stage drug discovery processes, the clinical trials is painful because large resources and time must have been consumed [1]. However, one way of increasing success rate in…

    -Norbert Nwankwo, Ignatius Okafor, Emmanuel Ibezim, Ngozika Njoku, Chinazor Nwankwo, Chioma Chinasa,