Journal of Bioinformatics, Computational and Systems Biology

Current Issue

  • Research article - Lifesciences Published: May 05, 2020

    Chip-seq and RNA-seq Data for the Identification of Functional Sub-pathways: A Proof of Consept in Lung Cancer

    High-throughput technologies, such as chromatin immunoprecipitation (ChIP) with massively parallel sequencing (ChIP-seq) have enabled cost and time efficient generation of immense amount of genome data. The advent of advanced sequencing techniques allowed biologists and bioinformaticians to investigate biological aspects of cell function and understand or reveal unexplored disease etiologies.

    -Xanthoula Atsalaki, Lefteris Koumakis, George Potamias, Manolis Tsiknakis

  • Research article - Lifesciences Published: Apr 20, 2020

    SARS-CoV-2 Pandemic, COVID-19 Case Fatality Rates and Deaths per Million Populations in India

    As of 3rd April 2020, India had 2547 cases of SARS-CoV-2 infections, with most cases in the states of Tamil Nadu, Kerala, Maharashtra and Delhi. While, foreign-travel-related incidents were the initial source of COVID-19 cases of the current pandemic in India, social transmission emerged rapidly later on. First COVID-19 deaths…

    -Joy Kumar Dey, and Sanjay Kumar Dey

  • Short communication - Lifesciences Published: Jun 23, 2019

    A Fully Annotated Genome Sequence of Human T-Cell Lymphotropic Virus Type 1 (HTLV-1)

    Human T-cell lymphotropic virus type 1 (HTLV-1) is present throughout the world and it is estimated that 5–10 million individuals are infected. This retrovirus has been mainly linked to Adult T Cell Leukemia/Lymphoma (ATLL), Tropical Spastic Paraparesis/HTLV-associated myelopathy (HAM/TSP) and infective dermatitis.

    -Fernanda K. Barreto, Thessika HA. Araújo, Filipe F. Almeida Rego, and Luiz CJ. Alcantara

  • Short communication - Lifesciences Published: Sep 28, 2019

    BiAnaCA: A Freely Accessible Tool for Data Analysis of End-Point Biochemical Assay

    In biomedical research, it is very common practice to carry out biochemical assays [1], ranging from simple end-point/kinetic assays to complex enzyme assays that are measured by a simple UV-Visible spectrophotometer or versatile multimode microplate readers [2]. The first step of assay is to measure absorbance (optical density), fluorescence [3],…

    -Abhikumar TT, Sujit RT, Sivakumar G, Venkateswara Rao A, Kulbhushan T, Prabha G and Prasad VB*

  • Short communication - Lifesciences Published: Sep 22, 2019

    Computational Non-Newtonian Hemodynamics of Small Vessels

    With the advancement of commercial Computational Fluid Dynamics (CFD) software [1], the use of non-Newtonian hemodynamic modelling is becoming more manageable. An excellent treatise has been provided by Steinman [2] with respect to the underlying assumptions of blood flow modelling.

    -Whitty J, Wain RA, Fsadni A and Francis J